Brainomix 360 Stroke imaging was utilized to improve and standardize the grading of baseline stroke severity, prior to treatment in patients enrolled in ArgenicaBrainomix 360 Stroke imaging was utilized to improve and standardize the grading of baseline stroke severity, prior to treatment in patients enrolled in Argenica

Brainomix AI Technology Reveals Efficacy of Novel Neuroprotective Drug Candidate in Severe Acute Ischemic Stroke Patients

  • Brainomix 360 Stroke imaging was utilized to improve and standardize the grading of baseline stroke severity, prior to treatment in patients enrolled in Argenica Therapeutic’s Phase II study of neuroprotective ARG-007
  • Brainomix AI core lab uses regulatory cleared stroke technology, alongside its foundation-model-powered imaging pipeline for clinical trials, to provide robust baseline phenotyping and efficacy analysis
  • The Brainomix AI-enabled analysis demonstrated efficacy of Argenica’s ARG-007 in severe stroke patients
  • Findings from the analysis will inform future clinical development and patient selection to advance treatment options for patients with severe acute ischemic stroke

CHICAGO and OXFORD, England, Dec. 18, 2025 /PRNewswire/ — Brainomix, a global leader and pioneer of AI-powered imaging biomarkers for stroke and lung fibrosis, today announced results from its partnership with Argenica Therapeutics (ASX: AGN) for imaging and clinical data analysis of the Phase II trial evaluating ARG-007, a neuroprotective agent for acute ischemic stroke. Analysis using Brainomix 360 Stroke, an FDA-cleared and CE-marked AI-imaging platform, confirmed statistically significant and clinically meaningful efficacy of ARG-007 in severe acute ischemic stroke patients through accurate and standardized quantification of digital imaging biomarkers, including e-ASPECTS which allowed for improved stratification of patients.

The analysis addressed a fundamental challenge in stroke clinical trials: variability in baseline stroke severity assessment. By applying standardized, objective AI imaging biomarkers to the trial data, Brainomix 360 Stroke confirmed that patients with larger infarcts (brain tissue death) at presentation experienced statistically significant improvements in neurological function at 24 hours and disability outcomes at 90 days when treated with ARG-007 compared with placebo. Brainomix also showed that these patients demonstrated significantly smaller final infarct volumes, a key hallmark of neuroprotection.

“This collaboration highlights the value of proactively incorporating AI-enabled precision imaging in clinical trial design and analysis of stroke research,” said Dr. Michalis Papadakis, CEO and co-founder of Brainomix. “Clinical trials in stroke rely heavily on accurate baseline assessments and manual scoring methods, which can introduce variability that obscures true treatment effects. Our Brainomix 360 Stroke platform provides standardized, objective measurements that help identify responsive patient populations with greater precision and, ultimately, accelerate the path to effective therapies for stroke patients. For ARG-007, by standardizing stroke assessment, AI removed variability and exposed a treatment effect that was previously hidden.”

Dr. Liz Dallimore, CEO and Managing Director of Argenica Therapeutics, added, “We are excited by the outcomes of this analysis from Brainomix. Their expertise and AI-enhanced imaging platform allowed us to gain deeper insights from our clinical trial data, providing greater clarity around treatment effects and enabling more detailed exploration of key biomarkers, and show that ARG-007 delivers real benefit where it is needed most, in patients with the largest, most disabling strokes.

“With AI, we can now design a next-phase study of ARG-007 using precision medicine principles, selecting patients based on objectively measured brain injury and maximizing the chance of meaningful recovery.”

About Brainomix 360 Stroke
Brainomix 360 Stroke is the world’s first fully automated AI imaging platform, specifically designed for acute stroke assessment across every stage of the patient pathway, facilitating more confident treatment and transfer decisions for patients in all hospitals, regardless of local resources or expertise. By integrating advanced algorithms for NCCT, CTA, CTP, and MRI, Brainomix 360 Stroke enables faster, more accurate diagnosis and empowers clinicians to make informed decisions that improve patient outcomes.

About Brainomix AI Core Lab
Brainomix AI core lab uses its regulatory cleared products, alongside next generation imaging and clinical analytics, to inform the interpretation of clinical trial data and provide insights from routinely collected trial imaging. Through improved baseline phenotyping and detailed analysis of imaging endpoints, including Brainomix’s next generation foundation model analysis, the AI core lab provides critical insights into therapeutic efficacy, safety and mechanisms of action at all stages of clinical development.

About Brainomix
Brainomix is a global pioneer in AI medical imaging, working with life science partners to support the clinical development novel therapeutics, as well as enabling precision medicine for better treatment decisions in stroke and lung fibrosis. Its flagship product, Brainomix 360 Stroke, is the world’s first fully automated AI-imaging platform, designed for acute stroke assessment at all points of the patient pathway, facilitating more confident treatment and transfer decisions for patients in all hospitals, regardless of local resources or expertise. Brainomix 360 e-Lung technology applies AI-driven CT biomarkers to identify, monitor, and predict disease progression in pulmonary fibrosis. Founded as a spinout from the University of Oxford, Brainomix has offices in the UK, Ireland and the USA, and operations in more than 20 countries.

To learn more about Brainomix and its technology visit www.brainomix.com, and follow us on TwitterLinkedIn and Facebook.

About Argenica Therapeutics

Argenica Therapeutics (ASX: AGN)  is a Perth-based biotechnology company developing innovative neuroprotective therapies to protect brain cells following stroke, traumatic brain injury, and other neurological conditions. Its lead drug candidate, ARG-007, is a novel neuroprotective peptide designed to limit brain tissue damage and improve recovery outcomes. ARG-007 has demonstrated efficacy in preclinical stroke, traumatic brain injury, and hypoxic-ischaemic encephalopathy models, and has completed Phase 1 and Phase 2 clinical trials in humans and is currently advancing toward a more targeted Phase 2b trial informed by the new AI analysis findings.

Contacts
Jeff Wyrtzen, Chief Marketing Officer
[email protected]
T +44 (0)1865 582730

US Media Enquiries
Jason Braco, Ph.D.
LifeSci Communications
[email protected]

UK & Europe Media Enquiries
Sue Charles
Charles Consultants
[email protected]

Logo – https://mma.prnewswire.com/media/1989193/5686544/Brainomix_Logo.jpg

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/brainomix-ai-technology-reveals-efficacy-of-novel-neuroprotective-drug-candidate-in-severe-acute-ischemic-stroke-patients-302645077.html

SOURCE Brainomix

Disclaimer: The articles reposted on this site are sourced from public platforms and are provided for informational purposes only. They do not necessarily reflect the views of MEXC. All rights remain with the original authors. If you believe any content infringes on third-party rights, please contact [email protected] for removal. MEXC makes no guarantees regarding the accuracy, completeness, or timeliness of the content and is not responsible for any actions taken based on the information provided. The content does not constitute financial, legal, or other professional advice, nor should it be considered a recommendation or endorsement by MEXC.

You May Also Like

Unprecedented Surge: Gold Price Hits Astounding New Record High

Unprecedented Surge: Gold Price Hits Astounding New Record High

BitcoinWorld Unprecedented Surge: Gold Price Hits Astounding New Record High While the world often buzzes with the latest movements in Bitcoin and altcoins, a traditional asset has quietly but powerfully commanded attention: gold. This week, the gold price has once again made headlines, touching an astounding new record high of $3,704 per ounce. This significant milestone reminds investors, both traditional and those deep in the crypto space, of gold’s enduring appeal as a store of value and a hedge against uncertainty. What’s Driving the Record Gold Price Surge? The recent ascent of the gold price to unprecedented levels is not a random event. Several powerful macroeconomic forces are converging, creating a perfect storm for the precious metal. Geopolitical Tensions: Escalating conflicts and global instability often drive investors towards safe-haven assets. Gold, with its long history of retaining value during crises, becomes a preferred choice. Inflation Concerns: Persistent inflation in major economies erodes the purchasing power of fiat currencies. Consequently, investors seek assets like gold that historically maintain their value against rising prices. Central Bank Policies: Many central banks globally are accumulating gold at a significant pace. This institutional demand provides a strong underlying support for the gold price. Furthermore, expectations around interest rate cuts in the future also make non-yielding assets like gold more attractive. These factors collectively paint a picture of a cautious market, where investors are looking for stability amidst a turbulent economic landscape. Understanding Gold’s Appeal in Today’s Market For centuries, gold has held a unique position in the financial world. Its latest record-breaking performance reinforces its status as a critical component of a diversified portfolio. Gold offers a tangible asset that is not subject to the same digital vulnerabilities or regulatory shifts that can impact cryptocurrencies. While digital assets offer exciting growth potential, gold provides a foundational stability that appeals to a broad spectrum of investors. Moreover, the finite supply of gold, much like Bitcoin’s capped supply, contributes to its perceived value. The current market environment, characterized by economic uncertainty and fluctuating currency values, only amplifies gold’s intrinsic benefits. It serves as a reliable hedge when other asset classes, including stocks and sometimes even crypto, face downward pressure. How Does This Record Gold Price Impact Investors? A soaring gold price naturally raises questions for investors. For those who already hold gold, this represents a significant validation of their investment strategy. For others, it might spark renewed interest in this ancient asset. Benefits for Investors: Portfolio Diversification: Gold often moves independently of other asset classes, offering crucial diversification benefits. Wealth Preservation: It acts as a robust store of value, protecting wealth against inflation and economic downturns. Liquidity: Gold markets are highly liquid, allowing for relatively easy buying and selling. Challenges and Considerations: Opportunity Cost: Investing in gold means capital is not allocated to potentially higher-growth assets like equities or certain cryptocurrencies. Volatility: While often seen as stable, gold prices can still experience significant fluctuations, as evidenced by its rapid ascent. Considering the current financial climate, understanding gold’s role can help refine your overall investment approach. Looking Ahead: The Future of the Gold Price What does the future hold for the gold price? While no one can predict market movements with absolute certainty, current trends and expert analyses offer some insights. Continued geopolitical instability and persistent inflationary pressures could sustain demand for gold. Furthermore, if global central banks continue their gold acquisition spree, this could provide a floor for prices. However, a significant easing of inflation or a de-escalation of global conflicts might reduce some of the immediate upward pressure. Investors should remain vigilant, observing global economic indicators and geopolitical developments closely. The ongoing dialogue between traditional finance and the emerging digital asset space also plays a role. As more investors become comfortable with both gold and cryptocurrencies, a nuanced understanding of how these assets complement each other will be crucial for navigating future market cycles. The recent surge in the gold price to a new record high of $3,704 per ounce underscores its enduring significance in the global financial landscape. It serves as a powerful reminder of gold’s role as a safe haven asset, a hedge against inflation, and a vital component for portfolio diversification. While digital assets continue to innovate and capture headlines, gold’s consistent performance during times of uncertainty highlights its timeless value. Whether you are a seasoned investor or new to the market, understanding the drivers behind gold’s ascent is crucial for making informed financial decisions in an ever-evolving world. Frequently Asked Questions (FAQs) Q1: What does a record-high gold price signify for the broader economy? A record-high gold price often indicates underlying economic uncertainty, inflation concerns, and geopolitical instability. Investors tend to flock to gold as a safe haven when they lose confidence in traditional currencies or other asset classes. Q2: How does gold compare to cryptocurrencies as a safe-haven asset? Both gold and some cryptocurrencies (like Bitcoin) are often considered safe havens. Gold has a centuries-long history of retaining value during crises, offering tangibility. Cryptocurrencies, while newer, offer decentralization and can be less susceptible to traditional financial system failures, but they also carry higher volatility and regulatory risks. Q3: Should I invest in gold now that its price is at a record high? Investing at a record high requires careful consideration. While the price might continue to climb due to ongoing market conditions, there’s also a risk of a correction. It’s crucial to assess your personal financial goals, risk tolerance, and consider diversifying your portfolio rather than putting all your capital into a single asset. Q4: What are the main factors that influence the gold price? The gold price is primarily influenced by global economic uncertainty, inflation rates, interest rate policies by central banks, the strength of the U.S. dollar, and geopolitical tensions. Demand from jewelers and industrial uses also play a role, but investment and central bank demand are often the biggest drivers. Q5: Is gold still a good hedge against inflation? Historically, gold has proven to be an effective hedge against inflation. When the purchasing power of fiat currencies declines, gold tends to hold its value or even increase, making it an attractive asset for preserving wealth during inflationary periods. To learn more about the latest crypto market trends, explore our article on key developments shaping Bitcoin’s price action. This post Unprecedented Surge: Gold Price Hits Astounding New Record High first appeared on BitcoinWorld.
Share
Coinstats2025/09/18 02:30
Ripple CTO Explains How The XRP Ledger ‘Will Take Over The World’

Ripple CTO Explains How The XRP Ledger ‘Will Take Over The World’

On a Token Relations webinar for the XRP ecosystem on Dec. 20, Ripple CTO David Schwartz was asked the sort of question that usually produces a tidy dashboard answer
Share
Bitcoinist2025/12/24 06:00
Pump.fun (PUMP) Has Spiked by 200%: Can the Rally Survive?

Pump.fun (PUMP) Has Spiked by 200%: Can the Rally Survive?

Between July and now, the price of Pumpfun (PUMP) has spiked by more than 200%. The rally has been strong, and the sentiment is still high. However, do we expect to continue seeing these highs, or is the price showing signs of crashing already? We will consider this by taking insights from a video by
Share
Coinstats2025/09/18 01:30